Paroxysmal cold hemoglobinuria: a case report

Case report: paroxysmal cold hemoglobinuria presenting during pregnancy

BACKGROUND Paroxysmal cold hemoglobinuria is caused by a biphasic IgG autoantibody that triggers complement-mediated intravascular hemolysis. Paroxysmal cold hemoglobinuria has not previously been reported to occur in association with pregnancy. CASE PRESENTATION We report a case of an 18 year old female who presented in early pregnancy with acute hemolytic anemia and a positive Donath-Landst...

[An adult case of idiopathic chronic paroxysmal cold hemoglobinuria].

概要 慢 性経過 を示 した特発 性発作性 寒冷血 色素尿症 の1成 人例を報 告 し,文 献 的考察 を加 え た.症 例 は41才,男 性.1978年 冬期,先 行す る熱性疾 患を伴 わず,寒 冷に曝露 した後暗 褐色尿 に気 付 き,以 後毎年同 様 の症状 を繰 り返 すため, 1984年1月 精査 目的にて 当科 入院.貧 血 な し, 肝脾 腫 な し.入 院時検査 所見 で,ヘ モ グロ ビン尿(+), Ehrlich指 試験(+), Rosenbach試 験 (+), Donath-Landsteiner試 験(+),抗 体価4倍 で あ り発 作性寒冷 血色素 尿症 と診 断 した.血 清梅 毒反応(-), TPHA(-)で,血 清抗体価 は マイ コプラス マ,ム ンプス,麻 疹,単 純ヘ ル ペス, EBウ イル スいずれ も陰性 ない し低値 を示 した.経...

Paroxysmal cold hemoglobinuria: report of a case with an exceptionally high thermal range Donath-Landsteiner antibody.

Paroxysmal nocturnal hemoglobinuria in systemic lupus erythematosus: a case report

INTRODUCTION Paroxysmal nocturnal hemoglobinuria is an acquired disorder of hemopoiesis and is characterized by recurrent episodes of intravascular hemolysis due to an increased sensitivity to complement-mediated hemolysis. Systemic lupus erythematosus with paroxysmal nocturnal hemoglobinuria is very rare. We report a case of paroxysmal nocturnal hemoglobinuria that developed in a patient with ...

Case Report Posterior reversible encephalopathy syndrome following paroxysmal nocturnal hemoglobinuria: a case report and literature review

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired disorder characterized by hemolytic anemia, marrow failure, and a high incidence of life-threatening venous thrombosis. It is subject to a considerable variety of complications like intestinal obstruction and visceral embolism. The current study firstly presents a 40-yearold male with a previous diagnosis of PNH who developed posterio...